发表论文

硕果累累

科技服务事业部学术研究硕果累累，先后在《Nature Genetics》、《Nature Communications》、《PNAS》、《Plant Cell》等国际顶级学术刊物发布论文数百篇，累计影响因子3000+，此外还拥有40余项专利和150余项软件著作权，多项经营指标连续多年保持100%以上增长率。以下为2018年度发表的论文题目及项目名称：

累计发表论文
1000+篇

累计影响因子
3000+分

SCI论文
100+种

.jpg

基因组

文献题目 年份 期刊 影响因子 合作单位
Reference genome sequences of two cultivated allotetraploid cottons, Gossypium hirsutum and Gossypium barbadense 2018 Nature Genetics 27.125 华中农业大学
Resequencing of 243 diploid cotton accessions based on an updated A genome identifies? the genetic basis of key agronomic traits 2018 Nature Genetics 27.125 中国农业科学院棉花研究所
Allele-defined genome of the autopolyploid sugarcane Saccharum spontaneumL. 2018 Nature Genetics 27.125 福建农林大学
N6-methyladenine DNA methylation in Japonica and Indica rice genomes and its association with gene expression, plant development and stress responses 2018 Molecular Plant 9.326 中国农业科学院生物技术研究所
Genome sequencing of rice subspecies and genetic analysis of recombinant lines reveals regional yield- and quality- associated loci 2018 BMC Biology 5.77 沈阳农业大学
Long-read sequencing and de novo genome assembly of Ammopiptanthus nanus , a desert shrub 2018 Giga Science 7.276 中央民族大学
Hypoxic and cold adaptation insights from the Himalayan marmot genome 2018 iScience 暂无（cell子刊） 西安交通大学
A genomic variation map provides insights into the genetic basis of spring Chinese cabbage(Brassica rapa ssp. pekinensis) selection 2018 Molecular Plant 9.326 北京市农林科学院蔬菜中心
Whole-genome resequencing of a world-wide collection of rapeseed accessions reveals genetic basis of their ecotype divergence 2018 Molecular Plant 9.326 浙江大学
The Chinese giant salamander exemplifies the hidden extinction of cryptic species 2018 Current Biology 9.251 中国科学院昆明动物研究所
Genome of an allotetraploid wild peanut Arachis monticola: a de novo assemble 2018 Giga Science 7.276 河南农业大学
Genome-Wide Association Study and Transcriptome Analysis Provide New Insights into the White/Red Earlobe Color Formation in Chicken 2018 Cellular Physiology and Biochemistry 5.5 华南农业大学

微生物

文献题目 年份 期刊 影响因子
Effects of individual and combined zinc oxide nanoparticle, norfloxacin, and
sulfamethazine contamination on sludge anaerobic digestion		 2018 Bioresource Technology 5.81
Lack of short-chain fatty acids and overgrowth of opportunistic pathogens define dysbiosis of neurom 2018 Multiple Sclerosis Journal 5.28
Effects of individual and complex ciprofloxacin, fullerene C60, and ZnO nanoparticles on sludge dige 2018 Bioresource Technology 5.81
Dynamics and diversity of microbial community succession during fermentation of Suan yu, a Chinese t 2018 Food Research International 3.52
Inhibition of microbial spoilage of grass carp (Ctenopharyngodon idellus)
fillets with a chitosan-based coating during refrigerated storage		 2018 International Journal of Food Microbiology 3.45
Protective Effects of Salvianolic Acid A against Dextran Sodium Sulfate-Induced Acute Colitis in Rats 2018 Giga Science 4.19
Genome sequencing and comparative genomics
reveal the potential pathogenic mechanism of
Cercospora sojina Hara on soybean		 2018 DNA research 5.42

遗传群体

文献题目 年份 期刊 合作单位
TGW3, a Majo QTL that Negatively Modulates Grain Length and Weight in Rice 2018 Molecula plant 中国水稻研究所等
STAYGREEN, STAY HEALTHY: a loss-of-susceptibility mutation in the STAYGREEN gene povides duable, broad-spectrum disease resistances for over 50 years of US cucumber production 2018 New Phytologist 威斯康辛大学园艺部、北京农林科学院等
Genome sequencing of ice subspecies and genetic analysis of ecombinant lines reveals regional yield- and quality associated loci 2018 BMC Biology 沈阳农业大学
The majo-effect QTL CsARN6.1 encodes an AAA-ATPase domain-containing protein that is associated with waterlogging stress tolerance through promoting adventitious root formation 2018 the Plant Jounal 扬州大学等
RAP codes for a GST anthocyanin transporter that is essential for the foliage and fruit coloration in strawberry 2018 Jounal of Expeimental Botany 华中农业大学等
High-density SNP-based QTL mapping and candidate gene sceening for yield-related blade length and width in Saccharina japonica (Laminariales, Phaeophyta) 2018 Scientific Repot 中科院海洋所等
QTL Mapping Combined With Bulked Segregant Analysis Identify SNP Markers Linked to Leaf Shape Traits in Pisum sativum Using SLAF Sequencing 2018 Fonties in Genetics 浙江省农科院等
High-Density Genetic Map Constuction and Identifcation of QTLs Controlling Oleic and Linoleic Acid in Peanut using SLAF-seq and SSRs 2018 Scientific Repot 山东省花生研究所等
Fine mapping and candidate gene sceening of the downy mildew resistance gene RPF1 in Spinach 2018 Theo Appl Genet 中国农科院蔬菜花卉研究所等
“Physical mapping and candidate gene pediction of fetility restorer gene of cytoplasmic male steility in cotton” 2018 BMC genomics 河北农林科学院
Constuction of a high-density genetic map and mapping of QTLs fo soybean (Glycine max) agronomic and seed quality traits by specific length amplified fragment sequencing 2018 BMC Genomics 山东农科院
High-density genetic map constuction and comparative genome analysis in asparagus bean 2018 Scientific Repot 四川农业大学等
QTL Mapping and Marker Identification for Sex-Determining: Indicating XY Sex Determination System in the Swimming Crab (Portunus trituberculatus) 2018 Fonties in Genetic 中国水产科学研究院黄海水产研究所等
SLAF-based high-density genetic map constuction and QTL mapping for major economic traits in sea urchin Strongylocentrotus intermedius 2018 Scientific Repots 大连海洋大学等
Construction of a high-density genetic map by RNA sequencing and eQTL analysis for stem length and diameter in Dendrobium (Dendrobium nobile × Dendrobium wardianum) 2018 Industial Cops & Products 广东省农科院等
Rapid identifcation of a stipe rust resistant gene in a space-induced wheat mutant using specifc locus amplifed fragment (SLAF) sequencing 2018 Scientific Repots 长江大学等
QTL Mapping for Fiber Quality and Yield Traits Based on Introgression Lines Derived from Gossypium hirsutum × G. tomentosum 2018 Intenational Jounal of Molecular Sciences 华中农业大学
Identifcation of a locus confering dominant resistance to maize rough dwarf disease in maize 2018 Scientific Repots 河北农林科学院
High-density genetic map constuction and quantitative tait loci identification for growth traits in (Taxodium distichum var. distichum × T. mucronatum) × T. mucronatum 2018 BMC Plant Biology 江苏省中国科学院植物研究所
Quantitative Trait Locus Mapping of Flowering Time and Maturity in Soybean Using Next-Generation Sequencing-Based Analysis 2018 Fonties in Plant Science 广州大学等
Identification of ecombination events in outbed species with next-generation sequencing data 2018 BMC Genomics 南京林业大学
“Fine Mapping and Identification of a Novel Phytophthora Root Rot Resistance Locus?RpsZS18 on Chomosome 2 in Soybean” 2018 Fonties in Plant Science 中国农业科学院
Physical mapping of the bluegained gene from Thinopyrum ponticum chromosome 4Ag and development of bluegrainrelated molecular markers and a FISH probe based on SLAFseq technology 2018 Theo Appl Genet 中科院遗传发育所等
Molecula marker assisted breeding and genome composition analysis of Zhengmai 7698, an elite winter wheat cultivar 2018 Scientific Repots 河南省农业科学院
“Development of Thinopyum ponticumspecifc molecula markers and FISH pobes based on SLAFseq technology” 2018 Planta 中科院遗传发育所等
“High-Density Genetic Map Construction and Stem Total Polysacchaide Content-Related QTL Exploation for Chinese Endemic Dendrobium (Orchidaceae)” 2018 Fonties in Plant Science 杭州师范大学等
“QTLs and candidate genes for downy mildew resistance conferred by intespecific gape (V. vinifera L. × V. amurensis Rupr.) crossing” 2018 Scientia Hoticultuae 沈阳农业大学
Improvement of Salt Tolerance Using Wild Rice Genes 2018 Fonties in Plant Science 宁夏农林科学院等
Identification of a lage SNP dataset in Laimichthys crocea using specific-locus amplified fragment sequencing 2018 Animal Genetics 浙江海洋大学
QTL Mapping of Fiber-Related Traits Based on a High-Density Genetic Map in Flax (Linum usitatissimum L） 2018 Fonties in Plant Science 黑龙江省农科院等
“Genetic analysis and gene mapping of a low stigma exposed mutant gene by high-thoughput sequencing” 2018 PLOS ONE 井冈山大学
Fine mapping and discovey of candidate genes for seed size in watermelon by genome survey sequencing. 2018 Scientific Repot 中国农科院郑州果树所
Sceening of Genes Related to Ealy and Late Flowering in Tree Peony Based on Bulked Segregant RNA Sequencing and Verification by Quantitative Real-Time PCR 2018 Molecules 河南科技大学等
Genetic mapping of anthocyanin accumulation elated genes in peppe fruits using a combination of SLAF-seq and BSA 2018 PLOS ONE 北京农林科学院蔬菜研究中心
“QTL mapping of downy and powdey mildew resistances in PI 197088 cucumbe with genotypingbysequencing in RIL population” 2018 Theoetical and Applied Genetics 威斯康辛大学园艺部
A high density SLAF-SNP genetic map and QTL detection fo fibe quality traits in Gossypium hirsutum 2018 BMC Genomics 西南大学
Construction of A High-Density Genetic Map and Mapping of Fruit Traits in Watermelon (Citrullus Lanatus L.) Based on Whole-Genome Resequencing 2018 Intenational Jounal of mMlecular Sciences 中国农科院郑州果树所
Identification of a Novel QTL for Panicle Length From Wild Rice (Oryza minuta) by Specific Locus Amplified Fragment Sequencing and High Density Genetic Mapping 2018 Fonties in Plant Science 长江大学等
Identification of novel QTL associated with soybean isoflavone content 2018 the Cop Jounal 中国农业科学院
Development of a High-Density Genetic Map Based on Specific Length Amplified Fragment Sequencing and Its Application in Quantitative Trait Loci Analysis for Yield-Related Traits in Cultivated Peanut 2018 Fonties in Plant Science 中国农科院油料所
Constuction of the first high-density genetic linkage map of pikeperch (Sander lucioperca) using specific length amplified fragment (SLAF) sequencing and QTL analysis of growth-related traits 2018 Aquacultue 苏州大学基础医学与生物科学学院
Constuction of a high-density genetic map and identifcation of QTLs for cucumber mosaic virus resistance in pepper (Capsicum annuum L.) using specifc length amplifed fragment sequencing (SLAF-seq) 2018 Beeding Science 湖北农科院
Constuction of a high-density genetic linkage map and QTL mapping of oleic acid content and three agronomic traits in sun?ower (Helianthus annuus L.) using specifc-locus amplifed fragment sequencing (SLAF-seq) 2018 Beeding Science 东北林业大学、黑龙江农科院
QTL mapping of soybean node numbes on the main stem and meta-analysis fo mining candidate genes 2018 Biotechnology & Biotechnological Equipment 东北农业大学等
Quantitative Tait Locus (QTL) Mapping of Sugar Yield-Related Traits in Sugar Beet (Beta vulgaris L.) 2018 Suga Tech 东北林业大学等
A fist attempt for genetic linkage map construction and growth related QTL mapping in Acipenser sinensis using Specific Length Amplified Fragment Sequencing (SLAF‐seq) 2018 Jounal of Applied Ichthyology 中国水产研究院长江水产研究所等
Candidate genes fo fist flower node identified in pepper using combined SLAF-seq and BSA 2018 PLOS ONE 北京农林科学院蔬菜研究中心等
High-density genetic map of Populus deltoides constucted by using specific length amplified fragment sequencing 2018 Tee Genetics & Genomes 南京林业大学等
Genetic analysis and QTL mapping of fuit-elated traits in wax gourd (Benincasa hispida) 2018 Euphytica 华南农业大学等
Fine mapping of majo QTLs fo alkaline tolerance at the seedling stage in maize (Zea mays L.) through genetic linkage analysis combined with high-throughput DNA sequencing 2018 Euphytica “吉林省农科院、东北农业大学”
QTL mapping and candidate gene mining fo soybean seed weight pe plant 2018 Biotechnology & Biotechnological Equipment 东北农业大学等

转录调控事业部

文献题目 年份 期刊 影响因子
RESISTANCE TO POWDERY MILDEW8.1 boosts pattern‐triggered immunity against multiple pathogens in Arabidopsis and rice 2018 Plant Biotechnol J 6.305
The developmental dynamics of the Populus stem transcriptome. 2018 Plant Biotechnol J. 6.305
The auxin receptor TIR1 homolog (PagFBL1) regulates adventitious rooting through interactions with Aux/IAA28 in Populus 2018 Plant Biotechnol J. 6.305
OsPRR37 confers an expanded regulation of the diurnal rhythms of the transcriptome and photoperiodic flowering pathways in rice 2018 Plant Cell Environ 6.173
Transcriptome analysis identifies azinc finger protein regulating starch degradation in kiwifruit 2018 Plant Phisiology 5.949
RAP codes for a GST anthocyanin transporter that is essential for the foliage and fruit coloration in strawberry. 2018 J Exp Bot 5.83
Systematic identification of long non-coding RNAs during pollen development and fertilization in Brassica rapa 2018 The Plant Journal 5.775
Genome-Wide Association Study and Transcriptome Analysis Provide New Insights into the White/Red Earlobe Color Formation in Chicken. 2018 Cell Physiol Biochem. 5.5
Integrated Analysis of MiRNA and Genes Associated with Meat Quality Reveals that Gga-MiR-140-5p Affects Intramuscular Fat Deposition in Chickens 2018 Cell Physiol Biochem. 5.5
CaGdt1 plays a compensatory role for the calcium pump CaPmr1 in the regulation of calcium signaling and cell wall integrity signaling in Candida albicans 2018 Cell Communication and Signaling 5.324
High-Concentrate Diet-Induced Change of Cellular Metabolism Leads to Decreases of Immunity and Imbalance of Cellular Activities in Rumen Epithelium 2018 Cell Physiol Biochem 5.104
Anthocyanins accumulation and molecular analysis of correlated genes by metabolome and transcriptome in green and purple asparaguses (Asparagus officinalis, L.) 2018 Food Chemistry 4.946
Characterization of Conserved and Novel microRNAs in Lilium lancifolium Thunb. by High-Throughput Sequencing 2018 SCI REP-UK 4.259
Identification of a locus conferring dominant resistance to maize rough dwarf disease in maize 2018 SCI REP-UK 4.259
Identification and characterization of microRNAs in tree peony during chilling induced dormancy release by high-throughput sequencing 2018 SCI REP-UK 4.259
Transcriptome analysis provides insights into xylogenesis formation in Moso bamboo (Phyllostachys edulis) shoot 2018 SCI REP-UK 4.259
De novo transcriptome assembly and differential gene expression analysis of the calanoid copepod Acartia tonsa exposed to nickel nanoparticles 2018 Chemosphere 4.208
High-throughput sequencing analysis revealed the regulation patterns of small RNAs on the development of A. comosus var. bracteatus leaves 2018 scientific reports 4.122
SMRT sequencing of full-length transcriptome of flea beetle Agasicles hygrophila (Selman and Vogt). 2018 Sci Rep. 4.122
Genome-wide analysis of circular RNAs in bovine cumulus cells treated with BMP15 and GDF9 2018 scientific reports 4.122
Transcriptomic and Ectoine Analysis of Halotolerant Nocardiopsis gilva YIM 90087T Under Salt Stress 2018 Frontiers in Microbiology 4.019
Comparative Transcriptome Analysis Between a Spontaneous Albino Mutant and Its Sibling Strain of Cordyceps militaris in Response to Light Stress 2018 Frontiers in Microbiology 4.019
Exploration of the Regulatory Mechanism of Secondary Metabolism by Comparative Transcriptomics in Aspergillus flavus 2018 Frontiers in Microbiology 4.019
Transcriptomic analyses of tributyltin-induced sexual dimorphisms in rare minnow (Gobiocypris rarus) brains 2018 Ecotoxicology and Environmental Safety 3.974
Hepatic transcriptome analysis of juvenile GIFT tilapia (Oreochromis niloticus), fed diets supplemented with different concentrations of resveratrol 2018 Ecotoxicol Environ Saf. 3.974
Comparison of gene co-networks reveals the molecular mechanisms of the rice (Oryza sativa L.) response to Rhizoctonia solani AG1 IA infection 2018 Functional & Integrative Genomics 3.889
Comparative expression analysis identifies the respiratory transition-related miRNAs and their target genes in tissues of metamorphosing Chinese giant salamander (Andrias davidianus). 2018 BMC Genomics 3.73
A DREB1 gene from zoysiagrass enhances Arabidopsis tolerance to temperature stresses without growth inhibition 2018 Plant Science 3.712
Analysis of the Coding and Non-Coding RNA Transcriptomes in Response to Bell Pepper Chilling 2018 International journal of Molecular Sciences 3.687
Whole-Transcriptome Sequence Analysis of Verbena bonariensis in Response to Drought Stress 2018 International journal of Molecular Sciences 3.687
Heterologous Expression of a Novel Zoysia japonica C2H2 Zinc Finger Gene, ZjZFN1, Improved Salt Tolerance in Arabidopsis 2018 Frontiers in Plant Science 3.678
De novo transcriptome assembly and analysis of differential gene expression following peptidoglycan (PGN) challenge in Antheraea pernyi 2018 Int J Biol Macromol 3.671
Physiological and RNA-seq analyses provide insights into the response mechanism of the Cf-10-mediated resistance to Cladosporium fulvum infection in tomato 2018 Plant Molecular Biology 3.543
VlbZIP30 of grapevine functions in dehydration tolerance via the abscisic acid core signaling pathway. 2018 Hortic Res. 3.368
Transcriptome analysis of sweet Sorghum inbred lines differing in salt tolerance provides novel insights into salt exclusion by roots 2018 Plant and Soil 3.306
Comparative transcriptome analysis to elucidate the enhanced thermotolerance of tea plants (Camellia sinensis) treated with exogenous calcium 2018 Planta 3.249
Comparative Transcriptome Analyses Uncover Key Candidate Genes Mediating Flight Capacity in Bactrocera dorsalis (Hendel) and Bactrocera correcta (Bezzi) (Diptera: Tephritidae) 2018 Int J Mol Sci 3.226
Comparative Transcriptome Analyses Reveal Potential Mechanisms of Enhanced Drought Tolerance in Transgenic Salvia Miltiorrhiza Plants Expressing AtDREB1A from Arabidopsis 2018 Int J Mol Sci 3.226
Transcriptome reveals B lymphocyte apoptosis in duck embryonic bursa of Fabricius mediated by mitochondrial and Fas signaling pathways 2018 Molecular Immunology 3.188
Characterization and expression analysis of g- and c-type lysozymes in Dabry’s sturgeon (Acipenser dabryanus) 2018 Fish & Shellfish Immunology 3.185
Do the toll-like receptors and complement systems play equally important roles in freshwater adapted Dolly Varden char (Salvelinus malma)? 2018 Fish & Shellfish Immunology 3.185
Comprehensive Analysis of long non-coding RNA and mRNA Expression Patterns in Sheep Testicular Maturation. 2018 Biol Reprod. 3.184

医学事业部

项目名称 年份 期刊 影响因子 合作单位
转录组测序研究色素性视网膜炎病变分子机制 2017 Scientific?Reports 5.228 温州医科大学眼科医院
重测序：使用CRISPR-Cas9技术敲除整合到宿主基因组中的HBV?DNA 2017 Frontiers?in?Cellular?and?Infection?Microbiology 5.218 解放军疾病预防控制所
小RNA测序：结核杆菌藏于巨噬细胞通过MicroRNA-20a靶向ATG7和ATG16L1躲避宿主攻击 2016 ?frontiers?in?cellular?and?infection?microbiology 5.218 宁夏医科大学
转录组测序：体外和体内TLR3的激活抑制感光细胞坏死 2017 Investigative?Ophthalmology?&?Visual?Science 3.427 温州医科大学眼科医院

毛囊不同部位转录组分析鉴别雄激素性脱发的功能模式

 2017

J INVEST DERMATOL

6.287

南方医科大学

转录组测序助力于小鼠视网膜退变过程中H3K27me3作用机制的研究

2018

 Cell Death & Disease

5.965

川大华西医院眼科

小RNA测序：ceRNA：lncRNA NEAT1通过miR-101-3p作为竞争性内源RNA机制调节上皮膜蛋白2的表达以抑制鼻咽癌迁移和抗辐射

 2017 Oncotarget

5.168

 ?川大华西医院

甲型流感病毒（IAV）和肺炎链球菌（SP）感染小鼠模型转录组测序分析

 2017

oncotarget

5.168

四川大学华西基础医学与法医学院微生物学教研室

人类颞叶皮层组织circRNA测序揭示颞叶癫痫新见解

 2018

Cellular Physiology and Biochemistry

5.104

首都医科大学附属北京天坛医院北京神经外科研究所病理生理学系

小鼠肠道微生物多样性和回肠结肠转录组测序揭示高盐HS诱导肾损伤机制

 2017

Exp Mol Med

5.063

南方医科大学

肿瘤细胞系转录组测序鉴定可再生的耐药相关失调基因

 2015

sci rep

4.259

福建医科大学基础医学院

转录组测序：基于CRISPR-Cas9对鼠感光细胞进行RP9基因敲除和突变研究RP病变分子机制

 2017

sci rep

4.259

温州医科大学附属眼视光医院

云平台外显子APP助力解析单侧眼组织缺损和视网膜裂症的家族遗传原因

 2017

Sci Rep

4.259

温州医科大学附属眼视光医院

lncRNA测序：成熟和未成熟大鼠垂体前叶lncRNA鉴定–各组3混1

 2017

Sci Rep

4.259

吉林大学

Lewis肺癌小鼠模型脾脏转录组测序揭示干扰素可诱导的p204蛋白抗肿瘤免疫应答机制

 2018

Sci Rep

 4.259

山东大学生命科学学院山东省动物细胞与发育生物学重点实验室

7对同卵双胞胎转录组测序WGCNA鉴定与BMI相关的模块及hub基因

 2017

BMC Genomics

3.729

青岛大学公共卫生学院

转录组测序：Toll样受体3激活启动体内和体外光感受器细胞死亡

 2017

INVEST OPHTH VIS SCI

3.303

温州医科大学附属眼视光医院

PCR产物测序：CRISPR-Cas9编辑HIV协同受体CCR5和CXCR4保护CD4 + T细胞免受HIV-1感染

 2017

Cell Biosci

3.294

武汉大学基础医学院

转录组测序揭示地榆提取物阻断结直肠癌细胞Wnt β-catenin信号通路

 2018

RSC ADV

3.108

中山大学药学院

cirRNA测序：不同发育阶段和不同被毛颜色小鼠毛皮皮肤circRNA鉴定及ceRNA网络构建

 2018

EXP DERMATOL

2.679

山西农业大学

雌激素受体β（ERβ）基因敲减大鼠骨髓间充质干细胞rBMSCs的circRNA表达分析

 2017

BIOCHEM BIOPH RES CO

2.466

暨南大学药学院

外显子组测序鉴定家族性扩张型心肌病致病基因

 2017

Medicine

1.803

首都医科大学附属北京朝阳医院基础医学研究中心

xxfseo.com